Lizzy Caplan (39)

Reagan Ridley (voice)

Clark Duke (36)

Brett Hand (voice)

Christian Slater (52)

Rand Ridley (voice)

Brett Gelman (45)

Magic Myc (voice)

John DiMaggio (53)

Glenn Dolphman (voice)

Tisha Campbell (53)

Gigi Thompson (voice)

Bobby Lee (50)

Dr. Andre Lee (voice)

Andy Daly (50)

J.R. Scheimpough (voice)

Chris Diamantopoulos (46)

ROBOTUS (voice)

William Jackson Harper (41)

Bryan Jacobsen / Bryan Bot (voice)

Ron Funches (38)

Mr. Mothman (voice)

Henry Winkler (75)

Melvin (voice)

Dan Lippert

Sasquatch (voice)

Michael-Leon Wooley (50)

Power Struggle MC (voice)

Adam Scott (48)

Ron Staedtler (voice)

Zachary Quinto (44)

Dr. Skullfinger (voice)

Timothy Simons (43)

Flat Earth Leader (voice)

Kate Micucci (41)

Charlie (voice)

Roger Craig Smith (46)

Buzz Aldrin (voice) / Keanu Reeves / Johnny Depp (voice)

Suzy Nakamura (47)

Tamiko Ridley (voice)

Patton Oswalt (52)

TSA Guard (voice)

Kayvan Novak (42)

The Pope (voice)

Carl Tart (32)

Tupac / Threepac / Fourpac (voice) / Sporelando / Security Guard (voice)

Shaggy 2 Dope (46)

Shaggy2Dope (voice)

Gary Cole (65)

Brett's father (voice) / Sitcom Dad / Male Cop (voice)

Violent J (49)

Violent J (voice)

James Adomian (41)

David Blaine (voice) / Jesse Ventura / Alex Jones (voice) / Additional Voices (voice) / Bouncer (voice)

Kevin Michael Richardson (56)

Zarthax Griswald-Walton / Lizard Gatekeeper / Bill / Bailiff ( voice)

Grey DeLisle (48)

Additional Voices (voice) / Kate / Kate's Tumor / News Anchor (voice) / Taylor Swift / Queen of England / Barb Schriek / Ellen Degeneres / Judge Judy (voice) / News Anchor (voice) / Nadia (voice)

Ana Gasteyer (54)

Dolores (voice)