Tom Waits (71)

The Narrator (voice)

Jimmi Simpson (45)

Detective David Mills (voice)

Da'Vine Joy Randolph (35)

Detective Gail Johnson (voice)

John C. Reilly (56)

Donovan Smith (voice)

Bebe Neuwirth (62)

Lady Andrea The Giant (voice)

Melissa Villaseñor (33)

Sister Mary Margaret (voice)

Kurtwood Smith (78)

Carpenter K. Smith (voice)

Tim Heidecker (45)

Mayor Kevin De Maximum (voice)

Chris Conrad (51)

Detective Nico Onasis (voice)

Julian Barratt (53)

The Most Dangerous Man in the World (voice)

Kristen Bell (41)

Donella Pecker (voice)

Luis Guzmán (64)

Rodrigo Smalls (voice)

Sunita Mani (34)

Detective Jaya Mukherjee (voice)

Caleb McLaughlin (19)

Trevor Johnson (voice)

Tim Meadows (60)

Jeff Thumb (voice)

Terry O'Quinn (69)

Captain Krieger (voice)

Dax Shepard (46)

Chris Pecker (voice)

Debra Winger (66)

Trish McSapphire (voice)

Jason Mantzoukas (48)

Tim Snodgrass (voice) / Second Flophouse Resident (voice)

Hana Mae Lee (32)

Christina Smalls (voice) / Passerby 1 (voice)

Alia Shawkat (32)

Little Grace (voice) / Woman's Voice (voice)

Damon Herriman (51)

Street Hustler Boy (voice) / First Motherless Three (voice) / First Flophouse Resident (voice)

Tony Fitzpatrick

Promoter Tip Snarski / Policeman Driver (voice)

Peter Moxley

Third Motherless Three / Young Hustler (voice)

Jermaine Fowler (33)

TMZ Operator / Second Young Hustler (voice)

John Moxley

Second Motherless Three / Fourth Young Hustler (voice) / Skeevy Underground Wrestling Announcer / Captain Dennison

Antoine McKay

Chinatown Devin / 254 Bouncer (voice) / Chinatown Devin / Passerby 2 / Pedestrian (voice)

Dana DeLorenzo (38)

Sissy Smith / Voice on Earpiece (voice)

Mike O'Connell

Anchor Man (voice) / Anchor Man / Arena Announcer / Man's Voice on Phone (voice)

Valerie Azlynn (40)

Space Bitch (voice)