Héctor Elizondo (82)

Dooka (voice)

Rita Moreno (87)

Dookess (voice)

Adam Devine (36)

Sam-I-Am (voice)

Michael Douglas (75)

Guy-Am-I (voice)

Ilana Glazer (32)

Eb (voice)

Diane Keaton (73)

Michellee (voice)

Keegan-Michael Key (48)

Narrator (voice)

Suzy Eddie Izzard (57)

Snerz (voice)

Patricia Clarkson (59)

Pam-I-Am (voice)

Jillian Bell (35)

Gluntz / Hayzel (voice)

Jeffrey Wright (53)

McWinkle (voice)

Rob Brydon (54)

Philip Trousers (voice) / Philip Trousers / Snalfred (voice)

Kevin Michael Richardson (55)

Gobo / Robababobrian (voice)

James Marsden (46)

Bo (voice)

Lombardo Boyar (45)

Patrol Zook / Fresco Dooka (voice) / Yook Guard / Guard 1 / Guard 4 (voice) / Lab Assistant / Patrol Zook (voice) / Guard / Zook Guard 2 / Patrol Zook 2 (voice) / Zook Soldier 1 / Zook Guard (voice)

Herbert Siguenza

Zook Guard 1 / Zook Guard 3 / Patrol Zook 1 (voice) / Zook Soldier 2 / Zook Guard / TV Announcer (voice) / Guard 2 / Guard 3 / Guard 5 (voice) / Patrol Yook (voice)

Gloria Calderón Kellett (44)

Guide / Fresco Dookess / Doctor (voice) / Smooth Female Voice (voice)

Gwendoline Christie (41)

Marilyn Blouse (voice)

Darren Criss (32)

Looka (voice)

Marques Ray (38)

Guy Watcher (voice)

Nika Futterman (50)

Crony 2 (voice) / Carol / Tiny Ancient Woman (voice) / Merchant (voice) / Waitress (voice) / Snotty Woman (voice) / Tinytopian Girl (voice) / Happy Kid (voice) / Receptionist (voice)

Chris Diamantopoulos (44)

Bean Counter (voice)

Dee Bradley Baker (57)

Chickeraffe (voice) / Dolphacuda (voice) / Camelope (voice)

Joe Hanna

Chef (voice)

Jeff Bennett (57)

Tinytopian 1 / Patrol Zook (voice) / Ma Snerz (voice)

Jeannie Elias (65)

Proprietress (voice) / Mrs. McGrisses (voice)

Kari Wahlgren (42)

Inventor #3 (voice) / Kid Ant (voice) / Female Passerby 2 (voice) / Do-Gooder (voice) / Fa Ma (voice)

Fred Tatasciore (51)

Yes Man (voice) / Jeremy (voice) / Grandpa (voice) / Patrol Zook / Thrasher (voice) / Schvizelton Neighbor 3 (voice) / Townsperson 1 (voice) / Emergency Worker 3 (voice) / Glurfsberg Cop 2 (voice) / Proprietor 6 (voice) / Zook Goon 1 (voice) / Flea (voice) / Boss (voice) / Pokie-McDokie Man / Cabbie Right (voice)

Tracy Morgan (50)

Fox (voice)

Keith Ferguson (47)

Crony 3 (voice) / Executive (voice) / Confused Employee (voice) / Carnie (voice) / Zook Goon 2 (voice) / Bus Announcer (voice) / News Anchor (voice) / Additional Biker 2 (voice) / Guard 1 / Hat Man (voice) / Inventor #2 (voice) / Patron 1 (voice)