Kiara Muhammad (13)

Doc McStuffins (voice)

Jaden Betts

Donny McStuffins (voice)

Kimberly Brooks (43)

Dr. Maisha McStuffins (voice) / Surfer Girl (voice)

Gary Anthony Williams (46)

Marcus McStuffins (voice) / Butch (voice)

Loretta Devine (62)

Nurse Hallie (voice) / Hattie (voice)

Robbie Rist (47)

Stuffy Filbert McStuffins (voice) / Snowpeep (voice)

Lara Jill Miller (44)

Lambie (voice) / Mayella (voice) / Hazel the Witch (voice) / Snowpeep (voice)

Jess Harnell (48)

Chilly (voice) / The Wicked King (voice) / The Wicked King / Buddy (voice) / The Dude / Rodriguez / Snowpeep (voice)

China Anne McClain (13)

Tisha McStuffins (voice)

Peter MacNicol (57)

Egghead (voice)

Rob Paulsen (56)

Sir Kirby (voice)

Kath Soucie (51)

Celeste (voice)

Kyla Kenedy (9)

Tamara (voice)

Jeffrey Nicholas Brown (36)

Bronty (voice) / Ben (voice) / Otis / Tumbleweed (voice)

Jack Conley (53)

Dragon-Bot (voice)

Laraine Newman (60)

Professor Hootsburgh (voice) / Southwest Sal (voice) / Trixie (voice) / Trina Triceratops (voice) / Southwest Sal / Snowpeep (voice) / Aurora / Professor Hootsburgh (voice) / Aurora (voice)

Wayne Knight (56)

Viewy Stewie (voice)

Audra McDonald (41)

Itty Bitty Bess (voice)

Julianne Buescher

Bella (voice)

Damienne Merlina

Flora (voice)

Grey DeLisle (38)

Dress-Up Daisy (voice) / Bouncy Babies (voice)

Adam Croasdell (31)

Wildlife Will (voice)

Mitchell Whitfield (47)

Oooey Gablooey (voice)

Tom Kenny (49)

Charlie / Purple Monster (voice) / Charlie (voice)

Derek Phillips (35)

Wyatt (voice)

Jamie Sara Lewis

Calamity / Cheyenne (voice)

Michael Gough (55)

Yul (voice) / Officer Pete (voice)

Zoe Pessin

Emmie (voice)

Michelle Campbell

Sadie (voice)

Jeff Fischer (43)

Lenny (voice)