Jay Pharoah (36)

Junior (voice)

Marsai Martin (19)

Grey (voice)

Gerald 'Slink' Johnson (51)

Dalvin (voice)

Yvette Nicole Brown (52)

Beverly (voice)

JB Smoove (58)

Reggie / Beverly Evans (voice)

Rashida Olayiwola

Lashes By Lisa (voice)

Bern Nadette Stanis (70)

Peaches (voice)

Jimmie Walker (76)

Jim Bean (voice)

Judy Alice Lee

Hi-Lo (voice)

Phil LaMarr (57)

Radiator / Q (voice) / Mr. Wade (voice)

Wanda Sykes (60)

Mrs. Likeigiveashit (voice)

Lil Rel Howery (44)

Skoochie (voice) / Gabriel (voice) / Gabriel / Pigeon #2 (voice)

Heidi Gardner (40)

Kari (voice) / White Lady (voice) / Elon's Mama / Zombie (voice) / Brittany / Guests (voice)

Da Brat (49)

Fran (voice) / Francine / Crowd (voice)

Wes Armstrong

Nerd / Eggs (voice)

Godfrey (54)

Jon Jon / Jesus (voice) / Jesus (voice) / Minnesota Matt / Jesus (voice) / Jon Jon (voice) / Grady Oscar Piles / Jon Jon / Cory / Jesus (voice) / DJ Cam-Wow / Wallet (voice)

Michael McDonald (59)

Officer Pappardelle (voice) / Elon Musk (voice) / Manfred / Flying Patriarchy / Guests (voice)

Jim Meskimen (64)

Bill Gates / Zombie (voice)

Tisha Campbell (55)

Delphine (voice) / Delphine / Meka / Parishioners (voice) / Meka / Crowd (voice)

Ego Nwodim (36)

Fire Captain Anita Hose / Spectators (voice) / Residents (voice) / Customer (voice) / BBL Shawnte (voice) / Adetutu / Rashida / Crowd (voice)

Cree Summer (54)

Mimi / Female Roach / Jumping Girl / Residents (voice) / Mimi / Ms. Moosie / Female Roach / Mrs. Johnson (voice) / Princess Hoo-Ha / Old Nurse / Eggs (voice) / Female Voice / Bambi / Crowd (voice) / Mr. Moosie / Black Girl Magic (voice) / Female Roach / One of the Flies / Parishioners (voice) / Mimi / Clerk (voice) / Mimi / Crowd / Residents / Female Roach (voice) / Mimi (voice) / Mimi / Kids / Spectators / Danielle (voice)

Gary Anthony Williams (58)

Officer Samuels (voice) / God (voice) / Remus / Romulus / Officer #1 / Officer #2 (voice) / Remus / Romulus / Residents (voice)

Vena E. (32)

Jackie (voice) / BBL Qiana (voice)

Affion Crockett (49)

Residents (voice) / Spectators (voice) / Maya Angelou Hologram / Clown (voice) / Kon Man Kadin (voice)

Gabrielle Dennis (42)

Kiana (voice) / Smooché / Residents (voice) / Jameeka / BBL Danita / Student (voice) / Smooché (voice)

Salli Saffioti (47)

Allison Whitemen (voice) / Bronwyn / Guests (voice) / Allison Whitemen / Jennifer (voice) / Hockey Mom (voice) / Allison Whitemen / Hipsters (voice)

Devon Shepard

Donte (voice) / Residents (voice) / Police Chief Dave O. Black / Spectators (voice) / Bouncer / Store Owner (voice) / Police Chief Dave O. Black (voice) / Donte / Police Chief Dave O. Black / Street Vendor (voice) / Mr. Schibel / Principal (voice)

Todd Haberkorn (41)

Officer Park (voice) / Jeff Bezos / Zombie (voice)

Lil Meech (23)

Quan (voice)

Rob Haze

Ugly-G (voice) / Kid / Spectators (voice)