The story of Palkon Ki Chhaon Mein 2 revolves around an orphan girl named Suman who wishes to lead a happy married life along with a loving family. Karan and Karthik are brothers of the same family and are close to each other. Suman's marriage gets fixed with Karthik, the eldest son of the family, but Suman and Karan fall in love with each other in the meantime.