A native of Central City, Colorado, Newmeyer is best known for directing a handful of films in the Our Gang series and for directing several Harold Lloyd movies. With Sam Taylor, Newmeyer co-directed Lloyd in films including Safety Last! (1923), Girl Shy (1924), and The Freshman (1925). Newmeyer also had an extensive directing and acting resume in other comedy short films. He appeared as an actor in 71 films between 1914 and 1923.